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Description

The different biosynthetic tissues allow melatonin to act as an intracellular mediator or paracrine signal, in addition to the described endocrine effects [4,9]

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The evolutionary conservation of core CCD enzymes across plant lineages, particularly the CCD4 and NCED clades, suggests broad potential for cross-species applications, though functional divergence in non-model species necessitates careful examination

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These patients had newly filled prescriptions for GLP-1 RAs, dipeptidyl peptidase-4 (DPP4) inhibitors, sodium-glucose cotransporter 2 (SGLT2) inhibitors or sulfonylurea between January 2014 and December 2021

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